What do Cholinergics do?

Cholinergic drug, any of various drugs that inhibit, enhance, or mimic the action of the neurotransmitter acetylcholine, the primary transmitter of nerve impulses within the parasympathetic nervous system—i.e., that part of the autonomic nervous system that contracts smooth muscles, dilates blood vessels, increases …

What are direct-acting Cholinomimetics?

Direct-acting cholinomimetics are drugs that act directly by stimulating cholinergic receptors. These drugs are divided into drugs that stimulate muscarinic (M-cholinoreceptors) or nicotinic (N-cholinoreceptors) receptors.

What is cholinergic antagonist?

The drugs in this group antagonize the effects of acetylcholine. Most of these drugs are antagonists directly at the nicotinic or muscarinic receptor. Some act on the ion channel associated with the nicotinic receptor, and still others block acetylcholine release.

What do Parasympathomimetics do?

Parasympathomimetics are a class of medications that activate the parasympathetic nervous system by mimicking or modifying the effects of acetylcholine.

What is the difference between direct and indirect-acting cholinergic drugs?

Examples of direct-acting cholinergic agents include choline esters (acetylcholine, methacholine, carbachol, bethanechol) and alkaloids (muscarine, pilocarpine, cevimeline). Indirect-acting cholinergic agents increase the availability of acetylcholine at the cholinergic receptors.

What are examples of cholinergic drugs?

Why cholinergic drugs are called Parasympathomimetic?

Drugs that activate muscarinic receptors in the peripheral nervous system are called parasympathomimetic drugs because they mimic the effects of acetylcholine on the parasympathetic nervous system.

Which drug shows Parasympatholytic action?


Drug Drug Description
Dicyclomine An antimuscarinic agent used to treat IBS.
Biperiden A muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs.
Cyclopentolate An anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing.