What is the meaning of the word pemphigoid?
Pemphigoid is a rare autoimmune disorder that can develop at any age, including in kids, but that most often affects the elderly. Pemphigoid is caused by a malfunction of the immune system and results in skin rashes and blistering on the legs, arms, and abdomen.
What does Acantholysis mean?
Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders.
What is the difference between pemphigus and pemphigoid?
Pemphigus affects the outer of the skin (epidermis) and causes lesions and blisters that are easily ruptured. Pemphigoid affects a lower layer of the skin, between the epidermis and the dermis, creating tense blisters that do not break easily.
What is pemphigus Neonatorum?
PEMPHIGUS NEONATORUM is a. disease of the new-born, in which. vesicles or blebs, usually flat on the top, appear with or without fever, on a per- fectly normal or reddened skin with.
What does pemphigoid mean in Latin?
History and Etymology for pemphigus New Latin, from Greek pemphig-, pemphix pustule.
Is pemphigus vulgaris the same as bullous pemphigoid?
Pemphigus vulgaris (i.e., pemphigus) and bullous pemphigoid (i.e., pemphigoid) are autoimmune disorders in which blistering of the skin is the primary symptom.
Does Grover’s disease spread?
Grover’s disease usually begins as small itchy red bumps on the back and chest, which may then spread to the upper limbs.
What does Hypergranulosis mean?
Hypergranulosis means an increased number of cells in the granular layer of the skin. The granular layer is found near the surface in a part of the skin called the epidermis.
Does stress cause pemphigoid?
For those of you who have any one of the pemphigus/pemphigoid (P/P) related skin diseases, stress is the number one factor in flare-ups occurring. The mind-body connection is very strong and stress encourages the antibodies to act up and give you more blisters.
What does pemphigoid look like?
Large blisters that don’t easily rupture when touched, often along creases or folds in the skin. Skin around the blisters that is normal, reddish or darker than normal. Eczema or a hive-like rash. Small blisters or sores in the mouth or other mucous membranes (benign mucous membrane pemphigoid)
How does pemphigus start?
Pemphigus vulgaris occurs when the immune system mistakenly makes antibodies against proteins in healthy skin and mucous membranes. The antibodies break down the bonds between the cells, and fluid collects between the layers of the skin. This leads to blisters and erosions on the skin.
What does vulgaris mean in Latin?
common
Vulgaris, a Latin adjective meaning common, or something that is derived from the masses of common people, may refer to: Vulgaris aerae, the Latin translation for the Common Era. Sermo vulgaris, the vulgar Latin.
What is the medical dictionary definition of pemphigoid?
1. Resembling pemphigus. 2. A disease resembling pemphigus but significantly distinguishable histologically (nonacantholytic) and clinically (generally benign course). A rare, persistent, autoimmune skin disease featuring large blisters that are sometimes intensely itchy.
Is there such a thing as a pemphigus?
Pemphigus and pemphigoid are rare. More research is needed. They are easy to misdiagnose. Pemphigus and pemphigoid are NOT contagious. Not by blood. Not by fluids. Not by anything. Pemphigus and pemphigoid are not genetic. Pemphigus and pemphigoid are rare, autoimmune diseases that affect a very small percentage of the population.
What are the mechanisms of bullous pemphigoid disease?
Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and in pemphigoid, the basal keratinocytes lose adhesion to the basement membrane. Pemphigus lesions are mediated directly by th …
How is pemphigoid similar to other autoimmune diseases?
( Discuss) (January 2019) Pemphigoid is a group of rare autoimmune blistering diseases of the skin, and mucous membranes. As its name indicates, pemphigoid is similar in general appearance to pemphigus, but, unlike pemphigus, pemphigoid does not feature acantholysis, a loss of connections between skin cells.