What are Supersecondary motifs?
Supersecondary structures, or motifs, are characteristic combinations of a secondary structure 10 to 40 residues in length that recur in different proteins. They bridge the gap between the less specific regularity of a secondary structure and the highly specific folding of a tertiary structure.
What is a motif in protein structure?
A motif is similar 3-D structure conserved among different proteins that serves a similar function. An example from the textbook shows a helix-turn-helix motif. This is a structure that is seen in unrelated proteins that bind DNA, so the presence of a helix-turn-helix motif is an indication of a protein’s function.
What is the difference between Supersecondary protein structure and protein motifs?
They are patterns that repeat in a lot of different places. Supersecondary structures are motifs that are made of several secondary structures. Some motifs are much smaller (pockets for holding ions are 3-4 amino acids long), or involve no secondary structure interactions (see SLMs).
How are Supersecondary structures formed?
It is formed by a beta hairpin changing direction with one strand having a glycine residue and the other strand having a beta bulge. Beta corners have no known function.
What is difference between domain and motif?
A motif is a short conserved sequence pattern associated with distinct functions of a protein or DNA. It is often associated with a distinct structural site performing a particular function. A domain is also a conserved sequence pattern, defined as an independent functional and structural unit.
Why is collagen a triple helix?
The Basic Structural Unit of Collagen Is a Triple Helix Because its abundance in tendon-rich tissue such as rat tail makes the fibrous type I collagen easy to isolate, it was the first to be characterized.
What are examples of motifs?
Examples of Motif in Narrative Writing
- A repeated reference or visual of shattered glass (something in life is about to break)
- Recurring dishonest characters (to cue up the discovery of an unfaithful spouse)
- A character who constantly misplaces things (as the loss of someone or something significant is on the horizon)
How do you identify motifs?
A motif is a recurring narrative element with symbolic significance. If you spot a symbol, concept, or plot structure that surfaces repeatedly in the text, you’re probably dealing with a motif. They must be related to the central idea of the work, and they always end up reinforcing the author’s overall message.
Are protein domains structural motifs?
A structural domain is an element of the protein’s overall structure that is stable and often folds independently of the rest of the protein chain. Like the PH domain above, many domains are not unique to the protein products of one gene, but instead appear in a variety of proteins.
What are protein motifs and domains?
Do domains contain motifs?
Domains are normally longer than motifs. A domain consists of more than 40 residues and up to 700 residues, with an average length of 100 residues. A domain may or may not include motifs within its boundaries. Examples of domains include transmembrane domains and ligand-binding domains.
Is a triple helix possible?
Based on the way a double-stranded DNA helix is formed, a triple-stranded helix would not be possible. Because this happens to both single strands of the original double-stranded helix, you end up with two new double-stranded helices when you started with just one.