Is xiapex still available in the UK?

Are there any non-operative treatments for Dupuytren’s Disease? Xiapex (SOBI) is now licensed within the UK. It is also known as XIAFLEX (collagenase clostridium histolyticum) in the USA. International studies have demonstrated encouraging results.

How much does the average Peyronie’s disease treatment cost?

The mean annual, per-individual cost of Peyronie’s disease treatment increased from $1,531 in 2007 to $10,339 in 2018. The cost increase was greatest for injectable therapies, which rose from $811 per individual in 2007 to $16,184 in 2018, a 19-fold increase.

Who is the best doctor for Peyronie’s disease?

Urologists are doctors who specialize in the treatment of men’s urological and sexual health conditions, like Peyronie’s disease.

What is xiapex used for?

XIAPEX® is a non-surgical treatment for Dupuytren’s contracture for adults with a stiffening of the rope-like cord that pulls the fingers towards the wrist. This is known as a palpable cord contracture.

Is there an alternative to Xiapex?

Unfortunately, Xiapex has been withdrawn from clinical use for Dupuytren’s disease for commercial reasons. This is very disappointing as it was proving to highly effective. Mike is able to offer alternatives including percutaneous needles fasciotomy (PNF) or open surgery.

Is Xiapex available on the NHS?

Anna Schurer, Chair of the British Dupuytren’s Society, said: “The British Dupuytren’s Society is delighted that after four years of meetings and deliberations, Xiapex will finally become routinely available for patients on the NHS across the UK.

How effective are injections for Peyronie’s?

Results: Pain resolved in 97% of the patients who presented with pain after a mean of 2.5 injections. After therapy, 76% reported a subjective decrease in curvature, 9.5% noted an increase and 14.5% remained unchanged. Of the treated patients 72% reported an improvement in the ability to engage in coitus.

How successful is surgery for Peyronie’s?

They found the overall success rate of surgery was 96%, compared with 66% with CCH and 48% with traction. At a decade post treatment, traction was the most cost-effective with an average per-patient cost of $883, compared to $11,419 for surgery and $33,628 for CCH.

What is the success rate of Xiaflex?

They found the overall success rate of surgery was 96%, compared with 66% with CCH and 48% with traction.

How is Xiapex used to treat Peyronie’s disease?

Xiapex Injection for Peyronie’s Disease. Injection of Xiapex into a Peyronie’s plaque, which is comprised mostly of collagen, may result in enzymatic disruption of the plaque. Following this disruption of the plaque, penile curvature deformity and patient bother caused by Peyronie’s disease are reduced.

Is there a non surgical treatment for Peyronie’s disease?

Based on current scientific evidence, Xiapex is the only non-surgical treatment that has a significant impact on the peyronie’s plaque and on average leads to a 35% reduction in penile curvature – however, the results vary significantly from patient to patient with some patients experiencing even greater improvements.

Why was Xiapex not approved by the NHS?

The NHS in Cambridgeshire and Peterborough have currently (2012) rejected the use of Xiapex, mainly on economic grounds and because there is no clinical trial data comparing Xiapex with established treatments such as surgery. (The main trials evaluating Collagenase compared it to injecting a placebo, not to surgery.)

Where can I get an injection of Xiapex?

Xiapex injections can only be performed by uro-andrologists that have received training specifically for administering and managing Xiapex. Do I need to be hospitalized? No. The injections take place in a consulting room in an outpatient basis and consist of four steps: