When do you use the Deauville score?
The Deauville five-point scale (Deauville 5PS) is an internationally-recommended scale for routine clinical reporting and clinical trials using FDG PET-CT in the initial staging and assessment of treatment response in Hodgkin lymphoma (HL) and certain types of non-Hodgkin lymphomas (NHL).
Is a Deauville score of 4 Bad?
In particular, international guidelines recommend using the Deauville criteria to assign patients a score of 1 through 5, indicating their response to treatment as revealed by PET imaging. (Negative PET images are scored as 1 or 2 and positive PETs are scored as 3, 4 or 5, depending on the level of uptake.)
Is Deauville 3 complete response?
In most situations where standard treatment will be given, a Deauville score (DS) of 3 represents a complete metabolic response (CMR). DS 3 has also proved to be the most reproducible threshold amongst reporters when interpreting PET scans in lymphoma patients.
What does a Deauville score of 3 mean?
Score 3: Uptake > mediastinum but ≤ liver. Score 4: Uptake moderately increased compared to the liver at any site. Score 5: Uptake markedly increased compared to the liver at any site. Score X: New areas of uptake unlikely to be related to lymphoma.
What does the uptake number on a PET scan mean?
Positron Emission Tomography Typically, a standardized uptake value (SUV), a quantity that incorporates the patient’s size and the injected dose, that is more than 2.0 is considered to be suggestive of malignancy, whereas lesions with SUVs less than this value are considered to be benign.
What does a Deauville score of 4 mean?
Score 4: Uptake moderately increased compared to the liver at any site. Score 5: Uptake markedly increased compared to the liver at any site. Score X: New areas of uptake unlikely to be related to lymphoma.
What does Deauville 3 mean?
Page 3. Deauville Criteria. Concern that MBP >2cm background < 2cm was. too low a threshold. Take account of varying FDG uptake during tx.
What is a complete metabolic response?
In our schema, a complete metabolic response (CMR) is defined as a return of FDG uptake in previously documented lesions to a level equivalent to, or less than, residual radioactivity in normal tissues within the organ in question.
What are the 5 point criteria for Deauville?
5 Point Scale /Deauville criteria 1. no uptake 2. uptake ≤mediastinum 3. uptake > mediastinum but ≤liver 4. moderately increased uptake compared to liver 5. markedly increased uptake compared to liver and/or new lesions Deauville Criteria
How are FDG-avid lesions rated on the Deauville scale?
Each FDG-avid (or previously FDG-avid) lesion is rated independently: no uptake or no residual uptake (when used interim) slight uptake, but equal to or below blood pool (mediastinum) uptake above mediastinal, but below or equal to uptake in the liver
What is the response to treatment based on PET-CT?
This article outlines the classification’s response to treatment based on PET-CT . Also included in the classification are staging and response to treatment based on CT. The Lugano classification recommends the Deauville five-point scale for reporting response by FDG PET-CT:
What’s the Deauville score for no metabolic response?
stable disease (SD), also called no metabolic response: a Deauville score of 4 or 5 without significant change in FDG uptake from baseline. progressive disease (PD): a Deauville score of 4 to 5 with increasing intensity compared to baseline or any interim scan and/or any new FDG-avid focus consistent with malignant lymphoma 7