What is Marinol FDA approved for?
Marinol is manufactured as a capsule containing THC in sesame oil; it is taken orally. It was approved by the FDA in 1985 for the treatment of nausea and vomiting associated with cancer chemotherapy.
Is dronabinol considered an opioid?
Background. Opioid dependence remains a significant public health problem worldwide with only three FDA-approved treatments, all targeting the mu-opioid receptor. Dronabinol, a cannabinoid (CB) 1 receptor agonist, is currently under investigation as a novel opioid withdrawal treatment.
What is the drug Marinol used to treat?
Dronabinol is used to treat nausea and vomiting caused by cancer chemotherapy. It is usually used when other drugs to control nausea and vomiting have not been successful.
How is Marinol taken?
MARINOL is usually taken 2 times each day, 1 hour before lunch and 1 hour before dinner. If you are elderly or unable to tolerate this dose of MARINOL, your doctor may prescribe MARINOL to be taken 1 time each day, 1 hour before dinner or bedtime to reduce your chance of having nervous system problems.
How long does it take for Marinol to kick in?
Both Marinol and generic dronabinol come in capsules of 2.5 mg, 5 mg, and 10 mg strengths. These medications take about 30 minutes to an hour to start working, with peak effects at 2 to 4 hours.
How quickly does Marinol work?
After oral administration, dronabinol has an onset of action of approximately 0.5 to 1 hours and peak effect at 2 to 4 hours. Duration of action for psychoactive effects is 4 to 6 hours, but the appetite stimulant effect of dronabinol may continue for 24 hours or longer after administration.
What do Dr. prescribe Marinol?
Marinol is used to treat loss of appetite that causes weight loss in people with AIDS. Marinol is also used to treat severe nausea and vomiting caused by cancer chemotherapy. It is usually given after medicines to control nausea and vomiting have been tried without success.
Is Marinol good for pain?
Aside from approved uses, Marinol has also been used in clinical trials for other medical conditions: Chronic pain. A small trial found Marinol could alleviate pain in patients with chronic pain of various causes. Treatment with Marinol versus morphine showed similar effectiveness.
Is dronabinol an ingredient in Marinol?
Dronabinol, the active ingredient in Marinol (dronabinol capsules, USP), is synthetic delta-9-tetrahydrocannabinol (delta-9-THC). Dronabinol is a light yellow resinous oil that is sticky at room temperature and hardens upon refrigeration. Dronabinol is insoluble in water and is formulated in sesame oil.
What medications stimulate appetite?
Explore Medication Options. If dietary measures fail to reverse weight loss, ask your health provider about medications that are known to stimulate the appetite. These include Megace (megestrol acetate), Reglan (metoclopramide), and cannabinoids such as medical marijuana and Marinol (dronabinol).