What is Apo B Apo A ratio?

The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk.

What is Apo A1 & B test?

Apolipoprotein A-1 (Apo A-1) and apolipoprotein B (Apo B) are used alongside other routine lipid tests to help determine an individual’s risk of developing CVD – not as a general population screen but rather where patients have a family history of heart disease &/or hyperlipidaemia to help determine the cause ( …

What does Apo A1 do?

Apolipoprotein A1 (ApoA1) is the primary protein associated with high-density lipoprotein (HDL) particles, and plays a central role in reverse cholesterol transport.

What does high apo A mean?

Your apolipoprotein A levels may be high if you: Have high levels of apolipoprotein (familial hyperalphalipoproteinemia) Have a genetic disorder called familial cholesteryl ester transfer protein deficiency, or CETP. Take medicines containing extra estrogens.

What causes high apo B?

Elevated levels of apo B correspond to elevated levels of LDL-C and to non-HDL-C and are associated with an increased risk of cardiovascular disease (CVD). Elevations may be due to a high-fat diet and/or decreased clearing of LDL from the blood.

Is A1 High apolipoprotein good?

High levels of apo A-I is considered protective and can be independent of HDL levels. There are some genetic disorders that lead to deficiencies in apo A-I (and therefore to low levels of HDL).

How is high Apo B treated?

Consuming less dietary fat and cholesterol and many more fiber-rich, whole plant foods, which is essentially the Pritikin Eating Plan, will greatly reduce the amount of chylomicrons and their atherogenic, apoB-48-containing lipoproteins in the blood.

What does a high apo B mean?

High levels of apo B indicate increased risk from heart disease. Many of the body’s cell receptors recognize apo B and promote the absorption of cholesterol into cells. This continued absorption finally leads to the formation of plaque that can cause vascular disease leading to heart disease.

What does a high apolipoprotein B mean?

Apolipoprotein B or Apo B is a major protein that forms the main component of low density lipoprotein complexes or LDL cholesterol. Apo B transports this LDL cholesterol, which is bad cholesterol and triglycerides to tissues and cells. High levels of apo B indicate increased risk from heart disease.

What is Apo A-I deficiency?

In summary, low high density lipoprotein levels due to apolipoprotein A-I deficiency exacerbated the development of atherosclerotic lesions in mice with elevated atherogenic lipoproteins. This mouse model mimics human conditions associated with low HDL levels and provides additional evidence for the anti-atherogenic role of apoA-I.