What does B cepacia bacteria cause?

B cepacia can produce severe lung infections in young people with cystic fibrosis, often late in the course of the disease. It is associated with blood infections (bacteremia) in premature babies who are hospitalized for long periods of time.

What is B cepacia cystic fibrosis?

Burkholderia cenocepacia is an opportunistic pathogen particularly dangerous for cystic fibrosis (CF) patients. It can cause a severe decline in CF lung function possibly developing into a life-threatening systemic infection known as cepacia syndrome.

Can cepacia be cured?

Burkholderia bacteria are often resistant to many antibiotics, which makes them difficult to treat once they infect the lungs. However, some species may be successfully treated with combinations of antibiotics. Basic infection prevention and control practices reduce the risk of getting or spreading B. cepacia.

What is B cepacia infection?

Burkholderia cepacia is an aerobic gram-negative bacillus found in various aquatic environments. B cepacia is an organism of low virulence and is a frequent colonizer of fluids used in the hospital (eg, irrigation solutions, intravenous fluids). B cepacia rarely causes infection in healthy hosts.

Can Burkholderia cepacia cause pneumonia?

Burkholderia (formerly Pseudomonas) cepacia complex is a known serious threat to patients with cystic fibrosis, in whom it has the potential to cause the fatal combination of necrotizing pneumonia, worsening respiratory failure, and bacteremia, known as Cepacia syndrome.

Why can’t you get a lung transplant with B cepacia?

cepacia complex before transplant are at higher risk for postoperative sepsis and death than patients infected with B. multivorans or other genomovars.

What’s the oldest person with CF?

Thanks to advances in DNA testing, doctors are identifying more and more people with CF for the first time well into their 50s, 60s, and 70s. The oldest person diagnosed with CF for the first time in the U.S. was 82, in Ireland was 76, and in the United Kingdom was 79.

Why can’t you get a lung transplant with B. cepacia?

Can normal people get B cepacia?

Populations susceptible to B. B. cepacia poses little medical risk to healthy people. However, people who have certain health problems like weakened immune systems or chronic lung diseases, particularly cystic fibrosis , may be more susceptible to infections with B. cepacia.

What is the illness CF?

Cystic fibrosis is an inherited condition that causes sticky mucus to build up in the lungs and digestive system. This causes lung infections and problems with digesting food.

What kind of bacteria is Burkholderia cepacia complex?

Burkholderia cepacia complex. Burkholderia cepacia complex ( BCC ), or simply Burkholderia cepacia, is a group of catalase -producing, lactose -non fermenting, Gram-negative bacteria composed of at least 20 different species, including B. cepacia, B. multivorans, B. cenocepacia, B. vietnamiensis, B. stabilis, B. ambifaria, B. dolosa,…

How big is a Burkholderia cepacia replicon?

The Burkholderia cepacia type- strain ATCC 25416 (genomovar I) is 8.1 Mb in length and is known to have four circular replicons. Its largest replicon contains 4 rrn operons and the other two megabase- sized replicons contain a single rrn operon each.

How to make Burkholderia cepacia selective supplement sr0189?

Suspend 18.25g of Burkholderia cepacia Agar Base in 500ml of distilled water, mix well and sterilise by autoclaving at 121°C for 15 minutes. Cool to 50°C and aseptically add the contents of one vial of Burkholderia cepacia Selective Supplement SR0189, reconstituted as directed. Mix well and distribute into sterile Petri dishes.

Can a Burkholderia pseudomallei be misidentified as a cepacia?

Burkholderia pseudomallei, rarely identified in the United States, has also been misidentified as B. cepacia [22]. Isolates with a presumptive identification of B. cepacia should be confirmed by an alternate method before release of the identification to the clinician.