What is the principle of fluid bed processor?
Fluid bed dryers work on the principle of fluidization, a process where a material is converted from a static solid-like state to a dynamic fluid-like state. In this process, hot gas or air is introduced through a perforated distribution plate into the area holding the material.
What is fluid bed processor?
Fluid Bed Processor is a very good technology to make granules from powder using top spray method. The technology is most suited as the same equipment can be used for top spray granulation, bottom spray coating & drying all 03 parameters in the same equipment thereby reducing the nos of equipment used for a process.
What does a fluid bed operator do?
As a Fluid Bed Dryer Operator, you will gain operational knowledge of operating and troubleshooting the fluid bed dryer and associated equipment (i.e. Granulator, Sieve Deck, Spray Nozzles, Rotary Feed Valves, Liquid Feed System).
What is fluid bed equipment?
Fluid or Fluidised bed dryer is a kind of equipment used extensively in the pharmaceutical industries to reduce the moisture content in raw ingredients like powder and granules. The solids are lifted from the bottom that are slightly wet in condition and are suspended in a stream of air (fluidized state).
What is the end point of FBD?
End Point in a wet granulation process is characterized by rheological properties of the wet mass such as density, viscosity etc which are in turn a function of particle size, shape and other physical properties.
How is FBD CFM calculated?
Flow rate = Velocity x Area of cross section. Total capacity required = 884 / 0.8 = 1105 m3/hr = 651 CFM.
What is fluidization process?
Fluidization (or fluidisation) is a process similar to liquefaction whereby a granular material is converted from a static solid-like state to a dynamic fluid-like state. This process occurs when a fluid (liquid or gas) is passed up through the granular material.
What is the endpoint of drying?
Fluidization activity affects the drying end point. This model provided median water content of granules and hence the drying end point. NIR to measure moisture in a batch process is now becoming a common occurrence. NIR provides the product moisture profile throughout the drying process.
What are problems of granulation?
Nevertheless, granulation poses numerous challenges due to high quality requirement of the formed granules in terms of content uniformity and physicochemical properties such as granule size, bulk density, porosity, hardness, moisture, compressibility, etc. together with physical and chemical stability of the drug.
What is a good CFM airflow?
A: Airflow quantifies the amount of air a ceiling fan delivers and is measured in CFM which stands for cubic feet per minute. Good CFM ranges from 4,000 to 5,000. Better ranges from 5,000 to 6,000. Best is over 6,000.
Is a higher CFM better?
Is a higher CFM better? A higher CFM is always better for your kitchen fan. You can always run a high CFM hood on lower settings. It provides great ventilation by moving a heavy amount of air per minute.
What is the purpose of fluidization?
Fluidization is defined as a method to keep solid particles floating in an upward direction (Figure 5) in a flow of gas or liquid. In freezing, fluidization occurs when particles of a similar shape and size are subjected to an upward stream of low-temperature air.
Which is the best method for a fluid bed processor?
2. BOTTOM SPRAY- The bottom-spray (Wurster) fluid-bed method is very popular in the pharmaceutical industry for drug layering and for coating to modify or control drug release. The hot air is passed through the fluidized bed, particulate material are lifted in air stream, solution/suspension sprayed on fluidized bed for granulation and coating.
What is the principle of a fluidized bed dryer?
The Principle of Fluidized Bed Dryer: If air is allowed to flow through a bed of solid powdered material in the upward direction with the velocity greater than the settling rate of the particles, the solid particles will be blown up and become suspended in the air stream.
How is a fluidized bed in a holding vessel created?
A fluidized bed occurs when a quantity of solid particles (generally contained in a holding vessel, most commonly a fluid bed processor) are placed under appropriate conditions to cause the mixture to behave as a fluid. This is typically done by forcing pressurized air, gas, or other fluids through the bed of solid particles.
What is the working principle of fluid bed granulation?
The Working Principle of Fluid Bed Granulator A study of fluidized bed granulation process shows that the process is generally the same irrespective of the machine design. This is because the position of fluid bed spray system is always the same. That is, you may opt for either a top spray granulation or side/tangential spray system.