What causes Phlyctenular keratoconjunctivitis?

Phlyctenular keratoconjunctivitis results from a hypersensitivity reaction to bacterial antigens, primarily staphylococcal, but tuberculosis (TB), Chlamydia, and other agents have been implicated. It is more common among children. Many patients also have blepharitis.

What is Phlyctenular?

Phlyctenular keratoconjunctivitis is a nodular inflammation of the cornea or conjunctiva that results from a hypersensitivity reaction to a foreign antigen.

How is Limbitis treated?

Final Treatment and Management: The patient required high-dose topical steroids in the form of Prednisolone q1h OD for resolution of her allergic limbitis. Due to limbal thinning, Prednisolone was eventually replaced with medroxyprogesterone, cyclosporine 1% and serum tears.

Which drugs are used in the treatment of Phlyctenular conjunctivitis?

Phlyctenular Keratoconjunctivitis:

  • Doxycycline (100mg orally once daily)
  • Prednisolone acetate 1.0% (twice daily drops)
  • TobraDex (Tobramycin and Dexamethasone) ointment nightly.

How do you treat Phlyctenules?

More specific treatment strategies for PKC include: Steroid drops for two weeks, or combination steroid/antibiotic drops if the patient exhibits significant corneal involvement of the phlyctenule. Dose the steroids q.i.d. for the first two weeks, followed by a slow taper during the subsequent two to three weeks.

What is a Phlyctenule in eye?

Roat. Last full review/revision May 2020| Content last modified May 2020. Phlyctenular keratoconjunctivitis is an eye disorder that involves an immune reaction of the cornea (the clear layer in front of the iris and pupil) and conjunctiva (the membrane that lines the eyelids and covers the white of the eye) to bacteria …

Does pinguecula affect vision?

Complications. A pinguecula alone rarely causes any serious complications. It typically does not affect vision, and it is not linked to other eye diseases or cancer. Some people are uncomfortable with the appearance of a pinguecula, however.

What is pinguecula in the eye?

Pinguecula is an abnormal growth of tissue on the conjunctiva, the clear membrane that covers the white of the eye. A pinguecula is a yellowish raised growth on the conjunctiva typically adjacent to the border where the colored part of the eye meets the white part of the eye.

What are the symptoms of phlyctenular keratoconjunctivitis?

Common symptoms are redness of the eye, blurred vision, sensitivity to bright light, a sensation of a foreign object trapped in the eye, and sometimes visible flakes of dead skin at the edges of the eyelids. Doctors diagnose phlyctenular keratoconjunctivitis based on the eye’s appearance.

What are the symptoms of PKC in the cornea?

When present, symptoms of PKC depend upon the location of the lesion. Conjunctival lesions usually present with mild to moderate symptoms, including foreign body sensation, tearing, photophobia, burning, and itching. Corneal lesions typically present with more severe symptoms of the same variety.

When do phlyctenules appear on the cornea?

Small, yellow-gray, raised bumps (called phlyctenules) appear at the limbus (the area where the conjunctiva attaches to the cornea), on the cornea, or on the conjunctiva. The bumps last for several days to 2 weeks.

What kind of pain does phlcytenulosis cause in the eye?

The clinical presentation of phlcytenulosis is dependent on the location of the lesion as well as the underlying etiology. Conjunctival lesions may cause only mild to moderate irritation of the eye, while corneal lesions typically may have more severe pain and photophobia.