What is the most powerful topical anesthetic?

Tetracaine is an ester derivative of PABA. Its lipid solubility and anesthetic efficacy was elevated by replacing a hydrogen of the p-amino group with a butyl. In fact, tetracaine is 5 to 8 times more efficacious than cocaine and is the most potent among dental topical anesthetics.

What is the strongest dental numbing agent?

AGENTS AVAILABLE IN MANY FORMS. Benzocaine is an FDA-approved drug that is available in various forms, concentrations and over-the-counter agents. In the 20% concentration, benzocaine gel is the most commonly used topical anesthetic in dentistry, with an onset time of 30 seconds and duration of five to 15 minutes.

Can you buy topical lidocaine over the counter?

Background: Topical anesthetics are commonly applied for a variety of indications. Several lidocaine-containing topical anesthetics are available for purchase over the counter (OTC).

What is the best over the counter topical anesthetic?

Many of these are also available in over-the-counter strength for home use:

  • lidocaine (Dermoplast, LidoRx, Lidoderm)
  • benzocaine (Solarcaine, Dermoplast, Lanacane)
  • pramoxine (Sarna Sensitive, Proctofoam, Prax)
  • dibucaine (Nupercainal, Rectacaine)
  • tetracaine (Ametop Gel, Pontocaine, Viractin)

Why should you not use benzocaine?

The FDA is taking action against the use of benzocaine products because they have the potential to cause a condition called methemoglobinemia. Methemoglobinemia is a potentially deadly condition that causes blood to carry less oxygen.

Is lidocaine 5% over-the-counter?

Nonprescription (over-the-counter) lidocaine (Absorbine Jr, Aspercreme, Lidocare, Salonpas, others) is also available to relieve minor pain in shoulders, arms, neck and legs in adults and children 12 years of age and older. Lidocaine is in a class of medications called local anesthetics.