What does Icteric plasma indicate?
Icteric serum is caused by the presence of excess bilirubin in the blood stream as a result of increased production (pre-hepatic) or inappropriate excretion (hepatic and post-hepatic).
What color is Icteric plasma?
Icteric serum or plasma varies in color from dark to bright yellow, rather than the normal straw color.
How does icterus affect lab results?
Visual inspection results for icterus showed more variations between technologists and compared to ordinal values. Conclusions: We have demonstrated that some of the chemistry analytes were affected by hemolysis, icterus and lipemia interferences. Generally, our results were consistent with manufacturer’s claims.
What analytes are affected by icterus?
Sixteen common analytes were studied: alanine aminotransferase (ALT), albumin (ALB), alkaline phosphatase (ALP), amylase (AMY), aspartate aminotransferase (AST), total cholesterol (CHOLT), creatinine (CREA, enzymatic method), fructosamine (FRUC), gamma‐glutamyl transferase (GGT), HDL cholesterol (HDLc), total iron ( …
What happens if you spin blood before it clots?
If specimen is centrifuged before clotting is complete, a fibrin clot will form on top of the cell. This finding is frequent in hemolyzed specimens. Also, the gel barrier may not be intact and could cause improper separation of serum and cells, possibly affecting test results.
Does hemolysis affect AST?
Results: Hemolysis interference affected lactate dehydrogenase (LD) and aspartate aminotransferase (AST) almost at undetectable hemolysis by visual inspection (plasma hemoglobin < 0.5 g/L). For the analytes interfered with hemolysis, new samples have to be requested.
What does Icteric sclera mean?
Anicteric sclera means that the white part of your eye is white and healthy in appearance. Icteric sclera means the white part of your eye is yellow, a sign of jaundice. A variety of conditions can cause jaundice, including problems with the liver, pancreas, or gallbladder.
Which is a high concentration of icteric plasma?
Icteric plasma samples have a high prevalence in samples from patients in the intensive care unit, as well as gastroenterology, surgical and pediatric patients. Concentrations of bilirubin greater than 2.5 mg/dL can lead to clinically relevant changes of anti-thrombin.
How does icteric plasma affect hemolysis and lipemia?
Icteric plasma samples have a high prevalence in samples from patients in the intensive care unit, as well as gastroenterology, surgical and pediatric patients. Concentrations of bilirubin greater than 2.5 mg/dL can lead to clinically relevant changes of anti-thrombin. Higher concentrations can interfere with other coagulation tests. 8
What does it mean when a blood specimen is icteric?
Hereof, what does it mean when a blood specimen is Icteric? Medical Definition of icterus index : a figure representing the amount of bilirubin in the blood as determined by comparing the color of a sample of test serum with a set of color standards an icterus index of 15 or above indicates active jaundice. — called also icteric index.
What causes the discolouration of icteric serum?
Intoxications: Phone Conversations. The final discolouration of the serum we are going to cover is icteric serum. Icteric serum is caused by the presence of excess bilirubin in the blood stream as a result of increased production (pre-hepatic) or inappropriate excretion (hepatic and post-hepatic).