Which is better exemestane or anastrozole?
The steroidal inhibitor exemestane is partially non–cross-resistant with nonsteroidal aromatase inhibitors and is a mild androgen and could prove superior to anastrozole regarding efficacy and toxicity, specifically with less bone loss.
Is Arimidex the same as Arimidex?
Anastrozole is the generic name for the trade name drug Arimidex®. In some cases, health care professionals may use the trade name Arimidex® when referring to the generic drug name Anastrozole. Drug Type: Anastrozole is an anti-cancer hormone therapy.
What is the success rate of anastrozole?
Three-year survival rate in the anastrozole arm was 98.8%, whereas in the letrozole arm it was 96.7% (p = 0.20).
When to use exemestane instead of anastrozole?
Prescribed for Breast Cancer. exemestane may also be used for purposes not listed in this medication guide. See the full anastrozole side effects document. See the full exemestane side effects document. The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. View glossary of terms.
What kind of steroid is formestane for breast cancer?
It is a 3-oxo-Delta (4) steroid, a 17-oxo steroid, a hydroxy steroid and an enol. It derives from a hydride of an androstane. Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Which is a better aromatase inhibitor, letrozole or anastrozol?
This study demonstrated that letrozole is a more potent aromatase inhibitor than anastrozole (aromatization suppression rates were > 99.1% vs 97%, P = .003, with confirmatory estrogen suppression data). The clinical relevance of this small difference, demonstrated at a level of inhibition that is so close to complete, remains uncertain.
What are the side effects of anastrozole off label?
May also be prescribed off label for Endometrial Cancer. Prescribed for Breast Cancer. exemestane may also be used for purposes not listed in this medication guide. See the full anastrozole side effects document. See the full exemestane side effects document.